Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CPB2 | Q96IY4 | 19/20 | 0.77 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.59 |
| ▸ | CPB1 | P15086 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3192887 | 1.00 | CPB2 (0.77) | CPB2CYP3A4CPB1 | |
| SCHEMBL3211133 | 0.87 | CPB2 (0.82) | CPB2CYP3A4CPB1 | |
| SCHEMBL3211162 | 0.87 | CPB2 (0.82) | CPB2CYP3A4CPB1 | |
| SCHEMBL3214490 | 0.87 | CPB2 (1.00) | CPB2CYP3A4CPB1 | |
| SCHEMBL3214467 | 0.87 | CPB2 (1.00) | CPB2CYP3A4CPB1 | |
| SCHEMBL3211486 | 0.86 | CPB2 (1.00) | CPB2CYP3A4CPB1 | |
| SCHEMBL27759891 | 0.86 | CPB2 (1.00) | CPB2CYP3A4CPB1 | |
| SCHEMBL3193208 | 0.85 | CPB2 (0.95) | CPB2CYP3A4CPB1 | |
| SCHEMBL3261853 | 0.85 | CPB2 (1.00) | CPB2CYP3A4CPB1 | |
| SCHEMBL3193237 | 0.85 | CPB2 (0.95) | CPB2CYP3A4CPB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389764-B2 | Urea and sulfamide derivatives as inhibitors of TAFIa | SANOFI (FR) | 2013-03-05 | — | — | US | claimed |
| CN-101553219-A | Urea and sulfamide derivatives as TAFIa inhibitors | SANOFI AVENTIS (FR) | 2009-10-07 | — | — | CN | claimed |