SCHEMBL14732609

SCHEMBL14732609

C=Cc1ccc(CCOC(=O)CCC)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP4F2 P78329 1/20 0.46
CYP4A11 Q02928 1/20 0.46
APP P05067 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
MET P08581 2/20 0.42
CA12 O43570 1/20 0.42
CA1 P00915 1/20 0.42
CA4 P22748 1/20 0.42
CA6 P23280 1/20 0.42
CA5A P35218 1/20 0.42
CA7 P43166 1/20 0.42
CA9 Q16790 1/20 0.42
CA14 Q9ULX7 1/20 0.42
CA5B Q9Y2D0 1/20 0.42
THRB P10828 4/20 0.42
LMNA P02545 1/20 0.41
L3MBTL1 Q9Y468 1/20 0.41
CYP4Z1 Q86W10 3/20 0.41
ALOX5 P09917 1/20 0.40
CYP4F11 Q9HBI6 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14732607 0.91 CYP4F2 (0.44) CYP4F2CYP4A11TDP1THRBLMNA
SCHEMBL18868396 0.88 APP (0.46) CYP4F2CYP4A11APPTDP1MET
SCHEMBL22373674 0.88 MET (0.44) CYP4F2CYP4A11APPTDP1MET
SCHEMBL19881301 0.87 CYP4F2 (0.40) CYP4F2CYP4A11APPTDP1THRB
SCHEMBL14732503 0.84 MEN1 (0.46) CYP4F2CYP4A11THRBLMNAL3MBTL1
SCHEMBL18868407 0.84 CA1 (0.46) CYP4F2CYP4A11APPTDP1MET
SCHEMBL6783435 0.83 CYP4F2 (0.49) CYP4F2CYP4A11TDP1THRBTHRA
SCHEMBL6777451 0.83 CYP4F2 (0.68) CYP4F2CYP4A11TDP1THRBLMNA
SCHEMBL18868398 0.82 TDP1 (0.45) APPTDP1METCA12CA1
SCHEMBL15603601 0.82 APP (0.50) CYP4F2CYP4A11APPTDP1MET

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8669029-B2 Reactive compound, charge transporting film, photoelectric conversion device, electrophotographic photoreceptor and method of producing the same, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-03-11 US disclosed
US-20130052573-A1 NOVEL REACTIVE COMPOUND, CHARGE TRANSPORTING FILM, PHOTOELECTRIC CONVERSION DEVICE, ELECTROPHOTOGRAPHIC PHOTORECEPTOR AND METHOD OF PRODUCING THE SAME, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2013-02-28 US disclosed