SCHEMBL14732698

SCHEMBL14732698

C=Cc1cccc(COCCOCCCC)c1

nearest known ligand 0.43

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.39
TP53 P04637 1/20 0.39
PLA2G4B P0C869 1/20 0.37
ALDH1A1 P00352 2/20 0.37
HPGD P15428 1/20 0.37
CYP3A4 P08684 1/20 0.37
TSHR P16473 1/20 0.37
TLR4 O00206 1/20 0.35
TLR2 O60603 1/20 0.35
L3MBTL1 Q9Y468 2/20 0.35
NAAA Q02083 1/20 0.35
ADRB2 P07550 1/20 0.33
ADRB1 P08588 1/20 0.33
ADRB3 P13945 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7871006 0.97 TDP1 (0.41) TDP1TP53PLA2G4BALDH1A1HPGD
SCHEMBL10071517 0.93 PLA2G4B (0.40) TDP1TP53PLA2G4BTSHRL3MBTL1
SCHEMBL10071510 0.91 PLA2G4B (0.42) TDP1TP53PLA2G4BTSHRL3MBTL1
SCHEMBL10071515 0.91 PLA2G4B (0.42) TDP1TP53PLA2G4BTSHRL3MBTL1
SCHEMBL7874175 0.88 TP53 (0.43) TDP1TP53PLA2G4BALDH1A1TSHR
SCHEMBL6389444 0.86 TP53 (0.42) TDP1TP53ALDH1A1TSHRNAAA
SCHEMBL10071521 0.84 TDP1 (0.40) TDP1TP53ALDH1A1HPGDL3MBTL1
SCHEMBL10071516 0.84 TDP1 (0.40) TDP1TP53ALDH1A1HPGDL3MBTL1
SCHEMBL7215750 0.83 TDP1 (0.42) TDP1TP53ALDH1A1TSHRL3MBTL1
SCHEMBL10071528 0.82 TDP1 (0.40) TDP1TP53PLA2G4BALDH1A1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20160085163-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2016-03-24 US disclosed
US-9182687-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2015-11-10 US disclosed
US-9034544-B2 Compound, charge transporting film, photoelectric conversion device, and electrophotographic photoreceptor using the compound, method of producing electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2015-05-19 US disclosed
US-9034543-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2015-05-19 US disclosed
US-9005855-B2 Electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2015-04-14 US disclosed
US-20140295337-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2014-10-02 US disclosed
US-8808952-B2 Composition for forming charge transporting film, electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-08-19 US disclosed
US-8808952-B2 Composition for forming charge transporting film, electrophotographic photoreceptor, process cartridge, and image forming apparatus FUJI XEROX CO., LTD. (JP) 2014-08-19 US disclosed
US-20140072906-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2014-03-13 US disclosed
US-20140072907-A1 ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2014-03-13 US disclosed
US-20130260295-A1 COMPOSITION FOR FORMING CHARGE TRANSPORTING FILM, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2013-10-03 US disclosed
US-20130260295-A1 COMPOSITION FOR FORMING CHARGE TRANSPORTING FILM, ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2013-10-03 US disclosed
US-20130052572-A1 COMPOUND, CHARGE TRANSPORTING FILM, PHOTOELECTRIC CONVERSION DEVICE, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR USING THE COMPOUND, METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS FUJI XEROX CO., LTD. (JP) 2013-02-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130052572-A1 COMPOUND, CHARGE TRANSPORTING FILM, PHOTOELECTRIC CONVERSION DEVICE, AND ELECTROPHOTOGRAPHIC PHOTORECEPTOR USING THE COMPOUND, METHOD OF PRODUCING ELECTROPHOTOGRAPHIC PHOTORECEPTOR, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS PDE6C, SLC9A2, SCNN1G TDP1 4336/4885TP53 4885/4885PLA2G4B 450/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.