Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.46 |
| ▸ | CCR8 | P51685 | 1/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 6/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.36 |
| ▸ | METAP2 | P50579 | 1/20 | 0.36 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.34 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.33 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | NOS1 | P29475 | 1/20 | 0.32 |
| ▸ | NOS2 | P35228 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14732923 | 0.85 | CCR1 (0.42) | CCR1CCR8IRAK4HSP90AA1KCNH2 | |
| SCHEMBL14733059 | 0.85 | CCR1 (0.42) | CCR1CCR8IRAK4HSP90AA1KCNH2 | |
| SCHEMBL14732969 | 0.84 | CCR1 (0.64) | CCR1CCR8IRAK4KCNH2METAP2 | |
| SCHEMBL14733034 | 0.84 | CCR1 (0.47) | CCR1CCR8IRAK4KDM4EKCNH2 | |
| SCHEMBL14733145 | 0.84 | IRAK4 (0.36) | CCR1CCR8IRAK4HSP90AA1 | |
| SCHEMBL14732900 | 0.82 | CCR1 (0.44) | CCR1CCR8IRAK4HSP90AA1KCNH2 | |
| SCHEMBL882865 | 0.80 | HSP90AA1 (0.38) | IRAK4HSP90AA1KDM4EKCNH2P2RX7 | |
| SCHEMBL3581561 | 0.79 | HSP90AA1 (0.54) | CCR1CCR8IRAK4HSP90AA1KDM4E | |
| SCHEMBL14877170 | 0.79 | HSP90AA1 (0.54) | CCR1CCR8IRAK4HSP90AA1KDM4E | |
| SCHEMBL874802 | 0.79 | HSP90AA1 (0.54) | CCR1CCR8IRAK4HSP90AA1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026866-A2 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-02-28 | — | — | WO | disclosed |