Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.31 |
| ▸ | CCR8 | P51685 | 1/20 | 0.31 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14733007 | 0.84 | CCR1 (0.46) | IRAK4CCR1CCR8HSP90AA1 | |
| SCHEMBL14733147 | 0.82 | CCR1 (0.41) | IRAK4FFAR1CCR1CCR8GAA | |
| SCHEMBL14733152 | 0.81 | NOS2 (0.44) | FFAR1CCR1CCR8 | |
| SCHEMBL14733133 | 0.81 | FFAR1 (0.36) | FFAR1CCR1CCR8HSP90AA1TGFBR1 | |
| SCHEMBL14732923 | 0.76 | CCR1 (0.42) | IRAK4CCR1CCR8HSP90AA1 | |
| SCHEMBL14733059 | 0.76 | CCR1 (0.42) | IRAK4CCR1CCR8HSP90AA1 | |
| SCHEMBL14733014 | 0.75 | GRM5 (0.34) | CCR1CCR8HSP90AA1 | |
| SCHEMBL14733158 | 0.74 | CCR1 (0.40) | FFAR1CCR1CCR8GAATGFBR1 | |
| SCHEMBL14733144 | 0.73 | TGFBR1 (0.32) | FFAR1TGFBR1 | |
| SCHEMBL10369024 | 0.73 | KCNH2 (0.43) | FFAR1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026866-A2 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-02-28 | — | — | WO | disclosed |