Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS1 | P29475 | 3/20 | 0.39 |
| ▸ | NOS2 | P35228 | 3/20 | 0.39 |
| ▸ | BACE1 | P56817 | 4/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.37 |
| ▸ | APP | P05067 | 2/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.36 |
| ▸ | ALOX5AP | P20292 | 2/20 | 0.35 |
| ▸ | FEN1 | P39748 | 2/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14732983 | 0.89 | KCNH2 (0.44) | KCNH2IRAK4 | |
| SCHEMBL22120171 | 0.84 | KCNH2 (0.52) | KCNH2 | |
| SCHEMBL30779745 | 0.80 | — | — | |
| SCHEMBL913399 | 0.80 | — | — | |
| SCHEMBL26538143 | 0.79 | KCNH2 (0.56) | KCNH2 | |
| SCHEMBL2962979 | 0.79 | KCNH2 (0.43) | KCNH2 | |
| SCHEMBL27835923 | 0.79 | HRH1 (0.42) | NOS1NOS2KCNH2ALOX5APFEN1 | |
| SCHEMBL9440177 | 0.77 | KCNH2 (0.68) | KCNH2 | |
| SCHEMBL1195883 | 0.75 | MEN1 (0.44) | NOS1NOS2BACE1KCNH2APP | |
| SCHEMBL21199960 | 0.75 | HSD11B1 (0.44) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026866-A2 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-02-28 | — | — | WO | disclosed |