Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.42 |
| ▸ | CCR8 | P51685 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.39 |
| ▸ | TGFBR1 | P36897 | 7/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | TGFBR2 | P37173 | 2/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | WNT3A | P56704 | 1/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14732997 | 0.90 | KCNH2 (0.36) | KCNH2NPC1RAB9A | |
| SCHEMBL14733134 | 0.86 | CCR1 (0.50) | CCR1CCR8GRM5TGFBR1KCNH2 | |
| SCHEMBL14732908 | 0.85 | CCR1 (0.42) | CCR1CCR8GRM5TGFBR1KCNH2 | |
| SCHEMBL14733157 | 0.84 | GRM5 (0.44) | CCR1CCR8GRM5TGFBR1KCNH2 | |
| SCHEMBL14733156 | 0.83 | GRM5 (0.49) | CCR1CCR8GRM5TGFBR1KCNH2 | |
| SCHEMBL14733132 | 0.83 | CCR1 (0.43) | CCR1CCR8GRM5TGFBR1KCNH2 | |
| SCHEMBL14733158 | 0.82 | CCR1 (0.40) | CCR1CCR8GRM5TGFBR1KCNH2 | |
| SCHEMBL14733005 | 0.82 | GRM5 (0.44) | CCR1CCR8GRM5TGFBR1 | |
| SCHEMBL14732969 | 0.81 | CCR1 (0.64) | CCR1CCR8GRM5TGFBR1KCNH2 | |
| SCHEMBL14733029 | 0.79 | NOS2 (0.44) | CCR1CCR8GRM5TGFBR1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013026866-A2 | NOVEL MICROBIOCIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2013-02-28 | — | — | WO | disclosed |