Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.70 |
| ▸ | MEN1 | O00255 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.70 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | PKM | P14618 | 2/20 | 0.59 |
| ▸ | THRB | P10828 | 1/20 | 0.59 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.44 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.44 |
| ▸ | PTPRB | P23467 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | CTSK | P43235 | 5/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8583632 | 0.98 | ATM (0.68) | ATMMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL15796605 | 0.90 | HTT (0.60) | ATMMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL8499239 | 0.83 | MAPT (1.00) | ATMMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL8498720 | 0.83 | MAPT (1.00) | ATMMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL8499578 | 0.83 | MAPT (1.00) | ATMMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL8496580 | 0.83 | MAPT (1.00) | ATMMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL8498186 | 0.83 | MAPT (1.00) | ATMMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL26447868 | 0.79 | PKM (0.47) | ATMMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL896025 | 0.78 | PKM (0.46) | ATMMEN1MAPTKMT2AL3MBTL1 | |
| SCHEMBL26447855 | 0.78 | PKM (0.46) | ATMMEN1MAPTKMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9345791-B2 | Ligands for targeting of S1P receptors for in vivo imaging and treatment of diseases | WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER (DE) | 2016-05-24 | — | — | US | disclosed |
| US-9345791-B2 | Ligands for targeting of S1P receptors for in vivo imaging and treatment of diseases | WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER (DE) | 2016-05-24 | — | — | US | disclosed |
| US-20140170067-A1 | NEW LIGANDS FOR TARGETING OF S1P RECEPTORS FOR IN VIVO IMAGING AND TREATMENT OF DISEASES | WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER (DE) | 2014-06-19 | — | — | US | disclosed |
| US-20140170067-A1 | NEW LIGANDS FOR TARGETING OF S1P RECEPTORS FOR IN VIVO IMAGING AND TREATMENT OF DISEASES | WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER (DE) | 2014-06-19 | — | — | US | disclosed |
| WO-2013026765-A1 | NEW LIGANDS FOR TARGETING OF S1P RECEPTORS FOR IN VIVO IMAGING AND TREATMENT OF DISEASES | WESTFAELISCHE WILHELMS-UNIVERSITAET MUENSTER (DE) | 2013-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140170067-A1 | NEW LIGANDS FOR TARGETING OF S1P RECEPTORS FOR IN VIVO IMAGING AND TREATMENT OF DISEASES | S1PR1, S1PR5, S1PR2 | ATM 4049/4885MEN1 1630/4885MAPT 3493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.