Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.58 |
| ▸ | SRR | Q9GZT4 | 2/20 | 0.51 |
| ▸ | PSAT1 | Q9Y617 | 2/20 | 0.51 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.50 |
| ▸ | ANPEP | P15144 | 1/20 | 0.50 |
| ▸ | ACP3 | P15309 | 1/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.47 |
| ▸ | PPARG | P37231 | 6/20 | 0.46 |
| ▸ | PPARA | Q07869 | 5/20 | 0.46 |
| ▸ | ABCC4 | O15439 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | IDO1 | P14902 | 1/20 | 0.45 |
| ▸ | AGXT | P21549 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.44 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7357350 | 1.00 | EPHX1 (0.58) | EPHX1SRRPSAT1TAAR1ANPEP | |
| SCHEMBL7357345 | 1.00 | EPHX1 (0.58) | EPHX1SRRPSAT1TAAR1ANPEP | |
| Hydrochloric Acid SCHEMBL30885862 | 0.98 | EPHX1 (0.56) | EPHX1SRRPSAT1TAAR1ANPEP | |
| Hydrochloric Acid SCHEMBL16932212 | 0.98 | EPHX1 (0.56) | EPHX1SRRPSAT1TAAR1ANPEP | |
| Hydrochloric Acid SCHEMBL16932213 | 0.98 | EPHX1 (0.56) | EPHX1SRRPSAT1TAAR1ANPEP | |
| Biphenyl SCHEMBL7890864 | 0.90 | EPHX1 (0.52) | EPHX1SRRPSAT1TAAR1ANPEP | |
| L-Phenylalaninol SCHEMBL81769 | 0.87 | EPHX1 (0.76) | EPHX1TAAR1ANPEPPTGS1 | |
| L-Phenylalaninol SCHEMBL2521 | 0.87 | EPHX1 (0.76) | EPHX1TAAR1ANPEPPTGS1 | |
| L-Phenylalaninol SCHEMBL87692 | 0.87 | EPHX1 (0.76) | EPHX1TAAR1ANPEPPTGS1 | |
| L-Phenylalaninol SCHEMBL177073 | 0.87 | EPHX1 (0.76) | EPHX1TAAR1ANPEPPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119528749-A | Synthesis method of (r) -tert-butyl (1- ([ 1,1' -biphenyl ] -4-yl) -3-hydroxy propane-2-yl) carbamate | 河北八亿时空药业有限公司 | 2025-02-28 | — | — | CN | claimed |
| CN-121825923-A | (S) -transaminase mutant and application thereof in preparation of (R) -3- ([ 1,1' -biphenyl ] -4-yl) -2-aminopropan-1-ol | 浙江大学 | 2026-04-10 | — | — | CN | disclosed |
| CN-121825923-A | (S) -transaminase mutant and application thereof in preparation of (R) -3- ([ 1,1' -biphenyl ] -4-yl) -2-aminopropan-1-ol | 浙江大学 | 2026-04-10 | — | — | CN | disclosed |
| CN-119528749-A | Synthesis method of (r) -tert-butyl (1- ([ 1,1' -biphenyl ] -4-yl) -3-hydroxy propane-2-yl) carbamate | 河北八亿时空药业有限公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-119528749-A | Synthesis method of (r) -tert-butyl (1- ([ 1,1' -biphenyl ] -4-yl) -3-hydroxy propane-2-yl) carbamate | 河北八亿时空药业有限公司 | 2025-02-28 | — | — | CN | disclosed |
| CN-115745841-B | Preparation method of sakubi-qu intermediate | 凯特立斯（深圳）科技有限公司 | 2024-04-16 | — | — | CN | disclosed |
| WO-2023206874-A1 | SACUBITRIL INTERMEDIATE, PREPARATION METHOD THEREFOR, AND USE THEREOF | 凯特立斯（深圳）科技有限公司 | 2023-11-02 | — | — | WO | disclosed |
| CN-116083497-A | Synthesis method of sakubi qu intermediate | 南通常佑药业科技有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-116083497-A | Synthesis method of sakubi qu intermediate | 南通常佑药业科技有限公司 | 2023-05-09 | — | — | CN | disclosed |
| CN-115745841-A | Preparation method of shakubiqu intermediate | 凯特立斯（深圳）科技有限公司 | 2023-03-07 | — | — | CN | disclosed |
| US-20160200665-A1 | SYNTHESIS OF BIPHENYLALANINOL VIA NOVEL INTERMEDIATES | DPX HOLDINGS B.V. (NL) | 2016-07-14 | — | — | US | disclosed |
| US-9139515-B2 | Synthesis of R-biphenylalaninol | DPX HOLDINGS B.V. (US) | 2015-09-22 | — | — | US | disclosed |
| US-9139515-B2 | Synthesis of R-biphenylalaninol | DPX HOLDINGS B.V. (US) | 2015-09-22 | — | — | US | disclosed |
| US-20150210632-A1 | NEW PROCESS | NOVARTIS AG (CH) | 2015-07-30 | — | — | US | disclosed |
| US-20150210632-A1 | NEW PROCESS | NOVARTIS AG (CH) | 2015-07-30 | — | — | US | disclosed |
| WO-2015024991-A1 | SYNTHESIS OF BIPHENYLALANINOL VIA NOVEL INTERMEDIATES | DPX HOLDINGS B.V. (NL) | 2015-02-26 | — | — | WO | disclosed |
| US-20140296559-A1 | SYNTHESIS OF R-BIPHENYLALANINOL | DSM FINE CHEMICALS AUSTRIA NFG. GMBH & CO KG (AT) | 2014-10-02 | — | — | US | disclosed |
| US-20140296559-A1 | SYNTHESIS OF R-BIPHENYLALANINOL | DSM FINE CHEMICALS AUSTRIA NFG. GMBH & CO KG (AT) | 2014-10-02 | — | — | US | disclosed |
| WO-2014032627-A1 | NEW PROCESS | ZHEJIANG JIUZHOU PHARMACEUTICAL CO., LTD (CN) | 2014-03-06 | — | — | WO | disclosed |
| WO-2013026773-A1 | SYNTHESIS OF R-BIPHENYLALANINOL | DSM IP ASSETS B.V. (NL) | 2013-02-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150210632-A1 | NEW PROCESS | MME, DNPEP, ACE | EPHX1 76/4885SRR 694/4885PSAT1 1374/4885 |
| US-20140296559-A1 | SYNTHESIS OF R-BIPHENYLALANINOL | CYP2B6, CYP2A6, CYP2D6 | EPHX1 725/4885SRR 517/4885PSAT1 2786/4885 |
| US-20160200665-A1 | SYNTHESIS OF BIPHENYLALANINOL VIA NOVEL INTERMEDIATES | CYP1B1, UGT1A1, UGT2B7 | EPHX1 499/4885SRR 680/4885PSAT1 969/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.