Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.56 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | NQO1 | P15559 | 1/20 | 0.42 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.41 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.41 |
| ▸ | NQO2 | P16083 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | TRAP1 | Q12931 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14733857 | 1.00 | SLC2A1 (0.56) | SLC2A1DHODHPDE4APDE4BPDE4C | |
| SCHEMBL14733918 | 0.98 | SLC2A1 (0.57) | SLC2A1DHODHPDE4APDE4BPDE4C | |
| SCHEMBL17256150 | 0.86 | SLC2A1 (0.57) | SLC2A1DHODHPDE4APDE4BPDE4C | |
| SCHEMBL580254 | 0.81 | HTR2A (0.49) | PDE4APDE4BPDE4CPDE4DHTR2A | |
| SCHEMBL580817 | 0.81 | HTR2A (0.49) | PDE4APDE4BPDE4CPDE4DHTR2A | |
| SCHEMBL580350 | 0.81 | HTR2A (0.49) | PDE4APDE4BPDE4CPDE4DHTR2A | |
| SCHEMBL581243 | 0.81 | HTR2A (0.49) | PDE4APDE4BPDE4CPDE4DHTR2A | |
| SCHEMBL580783 | 0.81 | HTR2A (0.49) | PDE4APDE4BPDE4CPDE4DHTR2A | |
| SCHEMBL14865277 | 0.80 | SLC2A1 (0.52) | SLC2A1DHODHKDM4EALDH1A1HPGD | |
| SCHEMBL5159304 | 0.79 | PDE4A (0.64) | SLC2A1DHODHPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2331552-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2013-02-27 | — | — | EP | disclosed |