Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.41 |
| ▸ | DHODH | Q02127 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14733857 | 0.80 | SLC2A1 (0.56) | SLC2A1KDM4EALDH1A1HPGDDHODH | |
| SCHEMBL14733975 | 0.80 | SLC2A1 (0.56) | SLC2A1KDM4EALDH1A1HPGDDHODH | |
| SCHEMBL14733918 | 0.78 | SLC2A1 (0.57) | SLC2A1KDM4EALDH1A1HPGDALOX5 | |
| SCHEMBL4772614 | 0.77 | ALDH1A1 (0.46) | KDM4EALDH1A1TNKS2MTNR1AMTNR1B | |
| SCHEMBL14445681 | 0.76 | HDAC1 (0.56) | PTGS2HDAC6 | |
| SCHEMBL12274312 | 0.75 | PPARG (0.58) | ALOX5PTGS2 | |
| SCHEMBL15562566 | 0.74 | TAAR1 (0.53) | ALDH1A1TNKS2ALOX5MTNR1AMTNR1B | |
| SCHEMBL27834259 | 0.74 | SLC2A1 (0.56) | SLC2A1KDM4EALDH1A1HPGDDHODH | |
| SCHEMBL16673014 | 0.74 | PTGS2 (0.46) | ALDH1A1ALOX5PTGS2LMNASMN1; SMN2 | |
| SCHEMBL17256150 | 0.73 | SLC2A1 (0.57) | SLC2A1KDM4EALDH1A1HPGDDHODH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2364321-B1 | HCV inhibitors | BRISTOL MYERS SQUIBB CO (US) | 2013-04-17 | — | — | EP | disclosed |