Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 1/20 | 0.48 |
| ▸ | TAS2R38 | P59533 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | CA2 | P00918 | 1/20 | 0.30 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.30 |
| ▸ | MMP12 | P39900 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19594545 | 0.78 | — | — | |
| SCHEMBL1408404 | 0.76 | — | — | |
| SCHEMBL25741926 | 0.76 | — | — | |
| SCHEMBL11019175 | 0.72 | CRBN (0.50) | CRBNTAS2R38LMNAALOX15BLM | |
| SCHEMBL22521694 | 0.72 | CRBN (0.50) | CRBNTAS2R38LMNAALOX15BLM | |
| SCHEMBL714084 | 0.68 | CRBN (0.35) | CRBNTAS2R38PTGS1 | |
| Diacetamide SCHEMBL4953257 | 0.68 | CRBN (0.69) | CRBNTAS2R38LMNAALOX15BLM | |
| SCHEMBL17919111 | 0.67 | ALDH1A1 (0.38) | CRBNTAS2R38 | |
| SCHEMBL29286885 | 0.66 | CRBN (1.00) | CRBNTAS2R38LMNAALOX15BLM | |
| SCHEMBL1696471 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2269993-B1 | 2-AMINOQUINAZOLINE DERIVATIVE | KYOWA HAKKO KIRIN CO LTD (JP) | 2013-02-27 | — | — | EP | disclosed |