Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8020079 | 0.80 | MAPK1 (0.34) | HTTKDM4EALDH1A1LMNAMAPK1 | |
| SCHEMBL9807051 | 0.78 | GLA (0.38) | HTTGLAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6345951 | 0.77 | GLA (0.41) | HTTGLAALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL26922197 | 0.75 | MAPK1 (0.32) | HTTMAPK1SMN1; SMN2 | |
| SCHEMBL10393962 | 0.74 | MAPK1 (0.34) | HTTMAPK1SMN1; SMN2 | |
| SCHEMBL22444361 | 0.73 | KDM4E (0.38) | HTTKDM4EJAK2ALDH1A1LMNA | |
| SCHEMBL23694611 | 0.70 | — | — | |
| SCHEMBL23694374 | 0.70 | KDM4E (0.34) | KDM4EALDH1A1 | |
| SCHEMBL23229404 | 0.70 | KDM4E (0.34) | KDM4EALDH1A1 | |
| SCHEMBL28141999 | 0.70 | GLA (0.34) | HTTGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027794-A1 | NOVEL COMPOUND AND USE THEREOF AS PDE10 INHIBITOR | 田辺三菱製薬株式会社 (JP) | 2013-02-28 | — | — | WO | disclosed |