Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HEXA | P06865 | 2/20 | 0.30 |
| ▸ | HEXB | P07686 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3457245 | 0.87 | MAPK1 (0.32) | MAPK1SMN1; SMN2HTTGAA | |
| SCHEMBL26922197 | 0.87 | MAPK1 (0.32) | MAPK1SMN1; SMN2HTTGAA | |
| SCHEMBL10393962 | 0.86 | MAPK1 (0.34) | MAPK1SMN1; SMN2HTTGAAHEXA | |
| SCHEMBL8016425 | 0.81 | MEN1 (0.34) | HTTGAAMEN1NPC1RAB9A | |
| SCHEMBL14734330 | 0.80 | HTT (0.36) | MAPK1SMN1; SMN2HTTKDM4EALDH1A1 | |
| SCHEMBL14734455 | 0.80 | MEN1 (0.34) | MAPK1SMN1; SMN2MEN1NPC1RAB9A | |
| SCHEMBL9621372 | 0.80 | KDM4E (0.32) | MAPK1SMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL10391849 | 0.76 | HTT (0.32) | HTTGAA | |
| SCHEMBL13093948 | 0.76 | — | — | |
| SCHEMBL31207803 | 0.76 | KDM4E (0.39) | MAPK1SMN1; SMN2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117486811-A | Method for selectively forming substituted pyrazines | R.J.雷诺兹烟草公司 | 2024-02-02 | — | — | CN | claimed |
| CN-110637012-B | Method for selectively forming substituted pyrazines | R.J.雷诺兹烟草公司 | 2023-11-24 | — | — | CN | claimed |
| CN-110637012-A | Process for selectively forming substituted pyrazines | R.J.雷诺兹烟草公司 | 2019-12-31 | — | — | CN | claimed |
| CN-104342633-B | Volatile dihydropyrazinyl and dihydropyrazine metal complexes | 弗萨姆材料美国有限责任公司 | 2017-07-04 | — | — | CN | claimed |
| US-20250122402-A1 | LONG SHELF-LIFE STABLE MASS POLYMERIZABLE POLYCYCLOOLEFIN COMPOSITIONS CONTAINING PYRIDINE LIGATED PALLADIUM COMPOUNDS | PROMERUS, LLC (US) | 2025-04-17 | — | — | US | disclosed |
| WO-2025047604-A1 | ANIMAL OIL/FAT FLAVOR-IMPARTING AGENT | 味の素株式会社 | 2025-03-06 | — | — | WO | disclosed |
| US-20240043391-A1 | METHOD FOR PRODUCING ALKYLPYRAZINES | SYMRISE AG (DE) | 2024-02-08 | — | — | US | disclosed |
| CN-117486811-A | Method for selectively forming substituted pyrazines | R.J.雷诺兹烟草公司 | 2024-02-02 | — | — | CN | disclosed |
| EP-4287848-A1 | METHOD FOR PRODUCING ALKYLPYRAZINES | Symrise AG (DE) | 2023-12-13 | — | — | EP | disclosed |
| CN-110637012-B | Method for selectively forming substituted pyrazines | R.J.雷诺兹烟草公司 | 2023-11-24 | — | — | CN | disclosed |
| CN-116806122-A | Process for the preparation of alkylpyrazine | 西姆莱斯有限公司 | 2023-09-26 | — | — | CN | disclosed |
| WO-2022167055-A1 | METHOD FOR PRODUCING ALKYLPYRAZINES | SYMRISE AG (DE) | 2022-08-11 | — | — | WO | disclosed |
| CN-110637012-A | Process for selectively forming substituted pyrazines | R.J.雷诺兹烟草公司 | 2019-12-31 | — | — | CN | disclosed |
| WO-2013027794-A1 | NOVEL COMPOUND AND USE THEREOF AS PDE10 INHIBITOR | 田辺三菱製薬株式会社 (JP) | 2013-02-28 | — | — | WO | disclosed |
| US-7964623-B2 | Tricyclic benzopyrane compound | NISSAN CHEMICAL INDUSTRIES LTD. (JP) | 2011-06-21 | — | — | US | disclosed |
| CN-1211473-C | Method for producing cigarette spicery made from extractive material of tobacco as raw material | HUABAO DEODORIZATION SCIENCE A (CN) | 2005-07-20 | — | — | CN | disclosed |
| CN-1415717-A | Method for producing cigarette spicery made from extractive material of tobacco as raw material | HUABAO DEODORIZATION SCIENCE A (CN) | 2003-05-07 | — | — | CN | disclosed |
| WO-2000022946-A1 | SMOKING ARTICLE HAVING INCREASED AMINO ACID CONTENT | R. J. REYNOLDS TOBACCO COMPANY (US) | 2000-04-27 | — | — | WO | disclosed |
| US-6030462-A | COMPRISES SELECTIVELY ENRICHED CONTENT OF AT LEAST ONE AMINO ACID SELECTED FROM THE GROUP CONSISTING OF SERINE, THREONINE AND ANALOGS THEREOF, AND IS SUBSTANTIALLY FREE OF EXOGENOUS NON-SUGAR MAILLARD-FUNCTIONAL CARBONYL COMPOUNDS | R.J. REYNOLDS TOBACCO COMPANY (US) | 2000-02-29 | — | — | US | disclosed |
| US-5413122-A | Method of providing flavorful and aromatic compounds | R. J. REYNOLDS TOBACCO COMPANY (US) | 1995-05-09 | — | — | US | disclosed |