Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.58 |
| ▸ | DHODH | Q02127 | 4/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | KDM6B | O15054 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | KDM4A | O75164 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | KDM4D | Q6B0I6 | 1/20 | 0.37 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3574223 | 0.82 | KDM5B (0.57) | KDM5BDHODHKDM4CKDM4EALDH1A1 | |
| SCHEMBL7985846 | 0.79 | KDM5B (0.54) | KDM5BDHODHKDM4CKDM4EALDH1A1 | |
| SCHEMBL28309875 | 0.79 | KDM5B (0.54) | KDM5BDHODHKDM4CKDM4EALDH1A1 | |
| SCHEMBL161825 | 0.72 | KDM5B (0.46) | KDM5BDHODHKDM4CKDM4EALDH1A1 | |
| SCHEMBL5769273 | 0.72 | KDM4E (0.52) | KDM5BKDM4CKDM4EALDH1A1MEN1 | |
| SCHEMBL4769775 | 0.72 | KDM5B (0.46) | KDM5BKDM4CKDM4EALDH1A1MEN1 | |
| SCHEMBL30616877 | 0.72 | ATR (0.48) | KDM5BALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL9616246 | 0.72 | DHODH (0.66) | DHODHKDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL6103736 | 0.71 | KDM5B (0.76) | KDM5BDHODHKDM4CKDM4EKMT2A | |
| SCHEMBL1623759 | 0.71 | SMN1; SMN2 (0.53) | KDM5BKDM4CKDM4EALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013027794-A1 | NOVEL COMPOUND AND USE THEREOF AS PDE10 INHIBITOR | 田辺三菱製薬株式会社 (JP) | 2013-02-28 | — | — | WO | disclosed |