Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14720925 | 0.85 | — | — | |
| SCHEMBL14720355 | 0.84 | ALOX5 (0.36) | KDM4E | |
| SCHEMBL14720709 | 0.83 | TSHR (0.40) | — | |
| SCHEMBL8319536 | 0.75 | — | — | |
| SCHEMBL19627144 | 0.73 | KDM4E (0.33) | KDM4E | |
| SCHEMBL8814744 | 0.70 | — | — | |
| SCHEMBL17359421 | 0.70 | TSHR (0.40) | — | |
| SCHEMBL21195521 | 0.69 | — | — | |
| SCHEMBL20817336 | 0.69 | — | — | |
| SCHEMBL3334129 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013028999-A1 | SMALL MOLECULE INDUCERS OF GDNF AS POTENTIAL NEW THERAPEUTICS FOR NEUROPSYCHIATRIC DISORDERS | THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK (US) | 2013-02-28 | — | — | WO | disclosed |