Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 10/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
| ▸ | FABP4 | P15090 | 1/20 | 0.30 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14737469 | 0.83 | HPGD (0.46) | HPGDALDH1A1LMNATDP1 | |
| SCHEMBL14736800 | 0.81 | HPGD (0.47) | HPGDALDH1A1KDM4ELMNATDP1 | |
| SCHEMBL2591573 | 0.78 | ALDH1A1 (0.51) | HPGDALDH1A1KDM4E | |
| SCHEMBL14737237 | 0.77 | HPGD (0.44) | HPGDALDH1A1KDM4ELMNATDP1 | |
| SCHEMBL2584293 | 0.76 | GSK3B (0.38) | ALDH1A1 | |
| SCHEMBL2591578 | 0.76 | GSK3B (0.38) | ALDH1A1 | |
| SCHEMBL17613857 | 0.76 | GSK3B (0.40) | HPGD | |
| SCHEMBL2592192 | 0.75 | GSK3B (0.38) | — | |
| SCHEMBL2591668 | 0.74 | GSK3B (0.36) | — | |
| SCHEMBL14734743 | 0.74 | GSK3B (0.36) | HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2563770-A1 | BIARYL PHOSPHODIESTERASE INHIBITORS | Leo Pharma A/S (DK) | 2013-03-06 | — | — | EP | claimed |