Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 5/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.59 |
| ▸ | MC4R | P32245 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.55 |
| ▸ | ACHE | P22303 | 1/20 | 0.55 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.54 |
| ▸ | CCR3 | P51677 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12013906 | 0.98 | SIGMAR1 (0.65) | SIGMAR1CYP3A4HSD17B10OPRL1MC4R | |
| SCHEMBL20684383 | 0.87 | SIGMAR1 (0.61) | SIGMAR1CYP3A4HSD17B10OPRL1MC4R | |
| SCHEMBL2262610 | 0.87 | CYP3A4 (0.56) | SIGMAR1CYP3A4HSD17B10OPRL1MC4R | |
| SCHEMBL4817148 | 0.87 | CYP3A4 (0.56) | SIGMAR1CYP3A4HSD17B10OPRL1MC4R | |
| Ammonia Solution, Strong SCHEMBL27704870 | 0.85 | CYP3A4 (0.59) | SIGMAR1CYP3A4HSD17B10OPRL1MC4R | |
| SCHEMBL653329 | 0.83 | OPRL1 (0.67) | SIGMAR1CYP3A4HSD17B10OPRL1MC4R | |
| SCHEMBL1994180 | 0.83 | SIGMAR1 (0.61) | SIGMAR1CYP3A4HSD17B10OPRL1MC4R | |
| SCHEMBL20137567 | 0.83 | SIGMAR1 (0.61) | SIGMAR1CYP3A4HSD17B10OPRL1MC4R | |
| SCHEMBL18563358 | 0.83 | SIGMAR1 (0.61) | SIGMAR1CYP3A4HSD17B10OPRL1MC4R | |
| SCHEMBL2708329 | 0.83 | SIGMAR1 (0.61) | SIGMAR1CYP3A4HSD17B10OPRL1MC4R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2565194-A1 | IMIDAZO[1,2-a]PYRIDINE DERIVATIVE | Astellas Pharma Inc. (JP) | 2013-03-06 | — | — | EP | disclosed |