Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | F7 | P08709 | 5/20 | 0.37 |
| ▸ | F3 | P13726 | 5/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | PPARD | Q03181 | 3/20 | 0.37 |
| ▸ | PPARA | Q07869 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2591807 | 1.00 | HMGCR (0.43) | HMGCRPOLBEPHX2PPARGALDH1A1 | |
| SCHEMBL2585837 | 1.00 | HMGCR (0.43) | HMGCRPOLBEPHX2PPARGALDH1A1 | |
| SCHEMBL2591804 | 1.00 | HMGCR (0.43) | HMGCRPOLBEPHX2PPARGALDH1A1 | |
| SCHEMBL2587903 | 1.00 | HMGCR (0.43) | HMGCRPOLBEPHX2PPARGALDH1A1 | |
| SCHEMBL11894515 | 1.00 | HMGCR (0.43) | HMGCRPOLBEPHX2PPARGALDH1A1 | |
| SCHEMBL2585839 | 1.00 | HMGCR (0.43) | HMGCRPOLBEPHX2PPARGALDH1A1 | |
| SCHEMBL1047023 | 1.00 | HMGCR (0.43) | HMGCRPOLBEPHX2PPARGALDH1A1 | |
| SCHEMBL11912386 | 0.91 | HMGCR (0.45) | HMGCRPOLBEPHX2PPARGALDH1A1 | |
| Potassium Ion SCHEMBL1077457 | 0.88 | FABP3 (0.39) | HMGCRFABP3 | |
| Potassium Ion SCHEMBL1077762 | 0.88 | FABP3 (0.39) | HMGCRFABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2563769-A1 | DIYNE COMPOSITIONS | EVOLVA AG (CH) | 2013-03-06 | — | — | EP | disclosed |