Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 4/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.37 |
| ▸ | F7 | P08709 | 5/20 | 0.37 |
| ▸ | F3 | P13726 | 5/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.37 |
| ▸ | PPARD | Q03181 | 3/20 | 0.37 |
| ▸ | PPARA | Q07869 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | OXER1 | Q8TDS5 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2591807 | 1.00 | HMGCR (0.43) | HMGCRPOLBEPHX2PPARGALDH1A1 | |
| SCHEMBL2585837 | 1.00 | HMGCR (0.43) | HMGCRPOLBEPHX2PPARGALDH1A1 | |
| SCHEMBL2591804 | 1.00 | HMGCR (0.43) | HMGCRPOLBEPHX2PPARGALDH1A1 | |
| SCHEMBL14735313 | 1.00 | HMGCR (0.43) | HMGCRPOLBEPHX2PPARGALDH1A1 | |
| SCHEMBL11894515 | 1.00 | HMGCR (0.43) | HMGCRPOLBEPHX2PPARGALDH1A1 | |
| SCHEMBL2585839 | 1.00 | HMGCR (0.43) | HMGCRPOLBEPHX2PPARGALDH1A1 | |
| SCHEMBL1047023 | 1.00 | HMGCR (0.43) | HMGCRPOLBEPHX2PPARGALDH1A1 | |
| SCHEMBL11912386 | 0.91 | HMGCR (0.45) | HMGCRPOLBEPHX2PPARGALDH1A1 | |
| Potassium Ion SCHEMBL1077457 | 0.88 | FABP3 (0.39) | HMGCRFABP3 | |
| Potassium Ion SCHEMBL1077762 | 0.88 | FABP3 (0.39) | HMGCRFABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8722910-B2 | Diyne compositions | EVOLVA AG (CH) | 2014-05-13 | — | — | US | claimed |
| EP-2563769-A1 | DIYNE COMPOSITIONS | EVOLVA AG (CH) | 2013-03-06 | — | — | EP | claimed |
| US-20120196822-A1 | Diyne Compositions | EVOLVA AG (CH) | 2012-08-02 | — | — | US | claimed |
| WO-2011134538-A1 | DIYNE COMPOSITIONS | EVOLVA LTD (CH) | 2011-11-03 | — | — | WO | claimed |
| US-8722910-B2 | Diyne compositions | EVOLVA AG (CH) | 2014-05-13 | — | — | US | disclosed |
| US-8722910-B2 | Diyne compositions | EVOLVA AG (CH) | 2014-05-13 | — | — | US | disclosed |
| US-8722910-B2 | Diyne compositions | EVOLVA AG (CH) | 2014-05-13 | — | — | US | disclosed |
| EP-2563769-A1 | DIYNE COMPOSITIONS | EVOLVA AG (CH) | 2013-03-06 | — | — | EP | disclosed |
| US-20120196822-A1 | Diyne Compositions | EVOLVA AG (CH) | 2012-08-02 | — | — | US | disclosed |
| US-20120196822-A1 | Diyne Compositions | EVOLVA AG (CH) | 2012-08-02 | — | — | US | disclosed |
| WO-2011134538-A1 | DIYNE COMPOSITIONS | EVOLVA LTD (CH) | 2011-11-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120196822-A1 | Diyne Compositions | OSR1, ERG28, OSBPL3 | HMGCR 2007/4885POLB 3706/4885EPHX2 3886/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.