SCHEMBL14735643

SCHEMBL14735643

Cc1cc(N2C(=O)N(CCCCCCCCCSCCCC(F)(F)C(F)(F)F)C(C)(C)C2=O)ccc1N[SH](=O)=O

nearest known ligand 0.41

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AR P10275 5/20 0.40
PGR P06401 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14735702 0.87 AR (0.40) ARPGR
SCHEMBL14735662 0.87 AR (0.39) ARPGR
SCHEMBL629441 0.87 AR (0.39) ARPGR
SCHEMBL630661 0.86 AR (0.44) ARPGR
SCHEMBL14735727 0.84 AR (0.39) ARPGR
SCHEMBL629334 0.82 AR (0.38) ARPGR
SCHEMBL629598 0.82 AR (0.41) ARPGR
SCHEMBL631033 0.81 AR (0.37) ARPGR
SCHEMBL629373 0.80 AR (0.49) ARPGR
SCHEMBL629322 0.80 AR (0.52) ARPGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2419410-B1 IMIDAZOLIDINE-2,4-DIONE DERIVATIVES, AND USE THEREOF AS A CANCER DRUG IPSEN PHARMA SAS (FR) 2013-03-06 EP disclosed