Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PER2 | O15055 | 1/20 | 0.41 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.41 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14820 | 0.84 | ESR1 (0.60) | ESR1SMN1; SMN2KMT2ATSHRMAPK1 | |
| SCHEMBL4483031 | 0.82 | ESR1 (0.55) | ESR1SMN1; SMN2KMT2ATSHRMAPK1 | |
| SCHEMBL9131891 | 0.81 | ESR1 (0.43) | ESR1SMN1; SMN2KMT2ATSHRMAPK1 | |
| SCHEMBL17333618 | 0.79 | ESR1 (0.58) | ESR1SMN1; SMN2KMT2ATSHRMAPK1 | |
| SCHEMBL27754450 | 0.78 | SMN1; SMN2 (0.47) | ESR1SMN1; SMN2KMT2ATSHRMAPK1 | |
| SCHEMBL7847115 | 0.78 | SMN1; SMN2 (0.49) | ESR1SMN1; SMN2KMT2ATSHRMAPK1 | |
| SCHEMBL10312352 | 0.77 | ESR1 (0.43) | ESR1SMN1; SMN2KMT2ATSHRMAPK1 | |
| SCHEMBL15702432 | 0.76 | HTT (0.41) | ESR1SMN1; SMN2KMT2ATSHRMAPK1 | |
| SCHEMBL4554082 | 0.75 | TSHR (0.56) | ESR1SMN1; SMN2KMT2ATSHRMAPK1 | |
| SCHEMBL18986175 | 0.75 | PTPN1 (0.40) | ESR1SMN1; SMN2KMT2AMEN1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1658076-B1 | ARYLOXY AND ARYLALKYLENEOXY SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES CO (US) | 2013-03-06 | — | — | EP | disclosed |