Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | PER2 | O15055 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.41 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.38 |
| ▸ | MMP9 | P14780 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10312364 | 0.85 | NR1I2 (0.56) | ESR1NR1I2LMNA | |
| SCHEMBL10312353 | 0.83 | PER2 (0.47) | SMN1; SMN2NR1I2KMT2AMEN1LMNA | |
| SCHEMBL15702432 | 0.80 | HTT (0.41) | ESR1SMN1; SMN2KMT2ATSHRMEN1 | |
| SCHEMBL27754450 | 0.80 | SMN1; SMN2 (0.47) | ESR1SMN1; SMN2KMT2ATSHRMEN1 | |
| SCHEMBL14820 | 0.78 | ESR1 (0.60) | ESR1SMN1; SMN2NR1I2KMT2ATSHR | |
| SCHEMBL14735895 | 0.77 | ESR1 (0.44) | ESR1SMN1; SMN2NR1I2KMT2ATSHR | |
| SCHEMBL4483031 | 0.77 | ESR1 (0.55) | ESR1SMN1; SMN2NR1I2KMT2ATSHR | |
| SCHEMBL9131891 | 0.76 | ESR1 (0.43) | ESR1SMN1; SMN2KMT2ATSHRMEN1 | |
| SCHEMBL10312346 | 0.76 | NPSR1 (0.52) | ESR1KMT2AMEN1LMNAALDH1A1 | |
| SCHEMBL17333618 | 0.74 | ESR1 (0.58) | ESR1SMN1; SMN2KMT2ATSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8828879-B2 | Silicon-containing composition having sulfonamide group for forming resist underlayer film | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2014-09-09 | — | — | US | disclosed |
| US-20120178261-A1 | SILICON-CONTAINING COMPOSITION HAVING SULFONAMIDE GROUP FOR FORMING RESIST UNDERLAYER FILM | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 2012-07-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120178261-A1 | SILICON-CONTAINING COMPOSITION HAVING SULFONAMIDE GROUP FOR FORMING RESIST UNDERLAYER FILM | STS, SI, MUS81 | ESR1 2543/4885SMN1; SMN2 3570/4885NR1I2 3866/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.