⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25405952 | 0.70 | DPP4 (0.37) | — | |
| SCHEMBL13324943 | 0.60 | ITGB1 (0.32) | — | |
| SCHEMBL25395345 | 0.55 | — | — | |
| SCHEMBL18654409 | 0.51 | — | — | |
| SCHEMBL12116389 | 0.51 | — | — | |
| SCHEMBL10764949 | 0.40 | — | — | |
| SCHEMBL6213386 | 0.40 | — | — | |
| Thiourea SCHEMBL50650 | 0.39 | — | — | |
| Thiourea SCHEMBL1395770 | 0.39 | NOS2 (0.36) | — | |
| SCHEMBL15703034 | 0.39 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2528900-B1 | SYNTHESIS OF SUBSTITUTED PYRAZOLINE CARBOXAMIDINE DERIVATIVES | ABBVIE BAHAMAS LTD (BS) | 2014-06-11 | — | — | EP | claimed |
| US-20130060041-A1 | SYNTHESIS OF SUBSTITUTED PYRAZOLINE CARBOXAMIDINE DERIVATIVES | ABBOTT HOSPITALS LIMITED (BS) | 2013-03-07 | — | — | US | claimed |
| US-20250026723-A1 | Cannabinoid Receptor Modulating Compounds | THE US SECRETARY DEPARTMENT OF HEALTH AND HUMAN (US) | 2025-01-23 | — | — | US | disclosed |
| US-9422244-B2 | Synthesis of substituted pyrazoline carboxamidine derivatives | ABBVIE BAHAMAS LTD. (BS) | 2016-08-23 | — | — | US | disclosed |
| EP-2528900-B1 | SYNTHESIS OF SUBSTITUTED PYRAZOLINE CARBOXAMIDINE DERIVATIVES | ABBVIE BAHAMAS LTD (BS) | 2014-06-11 | — | — | EP | disclosed |
| US-20130060041-A1 | SYNTHESIS OF SUBSTITUTED PYRAZOLINE CARBOXAMIDINE DERIVATIVES | ABBOTT HOSPITALS LIMITED (BS) | 2013-03-07 | — | — | US | disclosed |