Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 11/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 8/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 8/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 6/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 3/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 1.00 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3669138 | 1.00 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL14738478 | 1.00 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL14738411 | 1.00 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL14739330 | 1.00 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| Hydrochloric Acid SCHEMBL3732399 | 0.99 | SLC6A4 (0.97) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| Hydrochloric Acid SCHEMBL3743976 | 0.99 | SLC6A4 (0.97) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL17455375 | 0.86 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL20052823 | 0.86 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL17455219 | 0.86 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL20052783 | 0.86 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8507500-B2 | Inhibiting neurotransmitter reuptake | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2013-08-13 | — | — | US | disclosed |
| US-20130059864-A1 | INHIBITING NEUROTRANSMITTER REUPTAKE | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2013-03-07 | — | — | US | disclosed |