Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 10/20 | 1.00 |
| ▸ | SLC6A2 | P23975 | 9/20 | 1.00 |
| ▸ | SLC6A3 | Q01959 | 9/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 7/20 | 1.00 |
| ▸ | KCNH2 | Q12809 | 4/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.76 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.43 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.43 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 1/20 | 0.43 |
| ▸ | HRH1 | P35367 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17455375 | 1.00 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL17455164 | 1.00 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL20052823 | 1.00 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL17455219 | 1.00 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL20052836 | 1.00 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL14739005 | 0.86 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL14738478 | 0.86 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL14739330 | 0.86 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL3669138 | 0.86 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 | |
| SCHEMBL14738411 | 0.86 | SLC6A4 (1.00) | SLC6A4SLC6A2SLC6A3CYP2D6KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9944618-B2 | Inhibiting neurotransmitter reuptake | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2018-04-17 | — | — | US | disclosed |