Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 2/20 | 0.43 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.38 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.38 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
| ▸ | TUBB4A | P04350 | 3/20 | 0.35 |
| ▸ | TUBB | P07437 | 3/20 | 0.35 |
| ▸ | TUBA3C | P0DPH7 | 3/20 | 0.35 |
| ▸ | TUBA1B | P68363 | 3/20 | 0.35 |
| ▸ | TUBA4A | P68366 | 3/20 | 0.35 |
| ▸ | TUBB4B | P68371 | 3/20 | 0.35 |
| ▸ | TUBB3 | Q13509 | 3/20 | 0.35 |
| ▸ | TUBB2A | Q13885 | 3/20 | 0.35 |
| ▸ | TUBB8 | Q3ZCM7 | 3/20 | 0.35 |
| ▸ | TUBA3E | Q6PEY2 | 3/20 | 0.35 |
| ▸ | TUBA1A | Q71U36 | 3/20 | 0.35 |
| ▸ | TUBA1C | Q9BQE3 | 3/20 | 0.35 |
| ▸ | TUBB6 | Q9BUF5 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28435187 | 0.72 | ENPP2 (0.30) | ENPP2 | |
| SCHEMBL16684925 | 0.70 | — | — | |
| SCHEMBL3939053 | 0.70 | — | — | |
| SCHEMBL4411366 | 0.70 | — | — | |
| SCHEMBL28512047 | 0.70 | MCL1 (0.39) | ENPP2ORAI1ORAI2ORAI3CA1 | |
| SCHEMBL8014964 | 0.67 | — | — | |
| SCHEMBL186634 | 0.67 | — | — | |
| SCHEMBL5610234 | 0.65 | — | — | |
| SCHEMBL20829124 | 0.65 | — | — | |
| SCHEMBL203282 | 0.65 | ENPP2 (0.60) | ENPP2ORAI1ORAI2ORAI3CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2751263-A1 | COMPOSITIONS AND METHODS COMPRISING A LIPOLYTIC ENZYME VARIANT | Danisco US Inc. (US) | 2014-07-09 | — | — | EP | disclosed |
| WO-2013033318-A1 | COMPOSITIONS AND METHODS COMPRISING A LIPOLYTIC ENZYME VARIANT | DANISCO US INC. (US) | 2013-03-07 | — | — | WO | disclosed |