SCHEMBL14740722

SCHEMBL14740722

C=CCCC(C(=O)O)P(=O)(OCCCCCCCCCCCCCCCCCC)OCCCCCCCCCCCCCCCCCC

nearest known ligand 0.46

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PLA2G2C Q5R387 1/20 0.46
LPAR3 Q9UBY5 8/20 0.43
LPAR2 Q9HBW0 5/20 0.43
LPAR1 Q92633 4/20 0.42
P2RY10 O00398 5/20 0.41
TSHR P16473 3/20 0.37
GPR34 Q9UPC5 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2364791 0.79 LPAR3 (0.48) LPAR3LPAR2LPAR1P2RY10GPR34
SCHEMBL7152612 0.78 LPAR3 (0.49) LPAR3LPAR2LPAR1P2RY10GPR34
SCHEMBL7148541 0.78 LPAR3 (0.49) LPAR3LPAR2LPAR1P2RY10GPR34
SCHEMBL7153050 0.78 LPAR3 (0.49) LPAR3LPAR2LPAR1P2RY10GPR34
SCHEMBL5326687 0.74 GPR84 (0.47)
SCHEMBL4229201 0.74 GPR84 (0.47)
SCHEMBL13924959 0.74 GPR84 (0.47)
SCHEMBL10928491 0.72 LPAR3 (0.49) LPAR3LPAR2LPAR1
SCHEMBL11148243 0.72 PLA2G2C (0.48) PLA2G2CTSHR
SCHEMBL30695104 0.71 LPAR3 (0.59) LPAR3LPAR2LPAR1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2750711-A2 REMOTE ASSEMBLY OF TARGETED NANOPARTICLES USING H-PHOSPHONATE-ENE/-YNE HYDROPHOSPHONYLATION REACTIONS Mallinckrodt LLC (US) 2014-07-09 EP disclosed
WO-2013033450-A2 REMOTE ASSEMBLY OF TARGETED NANOPARTICLES USING H-PHOSPHONATE-ENE/-YNE HYDROPHOSPHONYLATION REACTIONS MALLINCKRODT LLC (US) 2013-03-07 WO disclosed