Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | CES1 | P23141 | 5/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 2/20 | 0.58 |
| ▸ | BCHE | P06276 | 2/20 | 0.58 |
| ▸ | CES2 | O00748 | 1/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | TTR | P02766 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | TGM2 | P21980 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CASP1 | P29466 | 1/20 | 0.45 |
| ▸ | HBB | P68871 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30817652 | 0.79 | ALDH1A1 (0.73) | ALDH1A1NPSR1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL30817653 | 0.79 | ALDH1A1 (0.73) | ALDH1A1NPSR1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL7479419 | 0.79 | ALDH1A1 (0.73) | ALDH1A1NPSR1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL7672585 | 0.77 | APP (0.52) | ALDH1A1GAAKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL7672581 | 0.77 | APP (0.52) | ALDH1A1GAAKDM4ESMN1; SMN2MEN1 | |
| SCHEMBL27806509 | 0.76 | CES1 (0.54) | ALDH1A1CES1NPSR1GAABCHE | |
| SCHEMBL2348974 | 0.75 | CES1 (0.73) | ALDH1A1CES1NPSR1GAABCHE | |
| SCHEMBL5707675 | 0.75 | MEN1 (0.48) | ALDH1A1CES1NPSR1GAABCHE | |
| SCHEMBL22394384 | 0.73 | CES1 (0.51) | ALDH1A1CES1NPSR1GAABCHE | |
| SCHEMBL28199867 | 0.73 | HSD17B10 (0.56) | ALDH1A1CES1NPSR1GAABCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119684105-A | N-phenyl isatin-mediated ketone-carboxylic acid conversion reaction method | 贵州医科大学 | 2025-03-25 | — | — | CN | disclosed |
| US-9598441-B2 | Therapeutic compounds and methods | WAYNE STATE UNIVERSITY (US) | 2017-03-21 | — | — | US | disclosed |
| US-20140221412-A1 | THERAPEUTIC COMPOUNDS AND METHODS | WAYNE STATE UNIVERSITY (US) | 2014-08-07 | — | — | US | disclosed |
| EP-2750508-A1 | THERAPEUTIC COMPOUNDS AND METHODS | Wayne State University (US) | 2014-07-09 | — | — | EP | disclosed |
| WO-2013033392-A1 | THERAPEUTIC COMPOUNDS AND METHODS | WAYNE STATE UNIVERSITY (US) | 2013-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140221412-A1 | THERAPEUTIC COMPOUNDS AND METHODS | XPOT, FANCI, XPO5 | ALDH1A1 196/4885CES1 655/4885NPSR1 3208/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.