Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.32 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | NEK1 | Q96PY6 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17597619 | 0.80 | TLR9 (0.35) | MTNR1AMTNR1BMEN1KMT2ADAO | |
| Hydrochloric Acid SCHEMBL17598109 | 0.79 | TLR9 (0.35) | MTNR1AMTNR1BMEN1KMT2ADAO | |
| SCHEMBL17597683 | 0.78 | KDR (0.38) | KDRKDM4EMEN1KMT2ATSHR | |
| SCHEMBL14745422 | 0.76 | PTGS2 (0.44) | PTGS2BRD4 | |
| SCHEMBL14744888 | 0.74 | GSK3B (0.44) | KDR | |
| Trifluoroacetic Acid SCHEMBL17598072 | 0.74 | KDR (0.36) | KDRKDM4ETSHR | |
| SCHEMBL14757693 | 0.73 | HDAC3 (0.35) | KDM4ETSHRDAO | |
| Hydrochloric Acid SCHEMBL14746173 | 0.73 | HDAC3 (0.34) | KDM4ETSHRDAO | |
| SCHEMBL14740831 | 0.73 | MEN1 (0.31) | MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL17597764 | 0.72 | MEN1 (0.30) | MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2750504-A1 | ANTIBACTERIAL COMPOUNDS AND METHODS FOR USE | PTC Therapeutics, Inc. (US) | 2014-07-09 | — | — | EP | disclosed |
| WO-2013033258-A1 | ANTIBACTERIAL COMPOUNDS AND METHODS FOR USE | PTC THERAPEUTICS, INC. (US) | 2013-03-07 | — | — | WO | disclosed |