Known targets — ChEMBL curated mechanism
ADORA1ADORA2AADORA2BADORA3PDE3APDE3BPDE4APDE4BPDE4CPDE4D
The experimentally established mechanism targets of Glycine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLRA1 | P23415 | 1/20 | 0.46 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.46 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.46 |
| ▸ | GABRR1 | P24046 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.30 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.30 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propionic Acid SCHEMBL5027758 | 0.86 | FFAR3 (0.50) | FFAR3TDP1 | |
| Beta-Alanine SCHEMBL14742146 | 0.85 | GABRP (0.38) | GABRR1LMNAFFAR3 | |
| Glycolic Acid SCHEMBL5027742 | 0.84 | FFAR3 (0.35) | FFAR3 | |
| Acetic Acid SCHEMBL5029629 | 0.83 | FFAR3 (0.37) | FFAR3TDP1 | |
| SCHEMBL14742333 | 0.80 | SLC1A3 (0.38) | SLC1A3SLC1A2SLC1A1TDP1 | |
| SCHEMBL15966 | 0.80 | — | — | |
| SCHEMBL4590681 | 0.80 | — | — | |
| SCHEMBL4591443 | 0.80 | — | — | |
| Aspartic Acid SCHEMBL14742503 | 0.78 | SLC1A3 (0.46) | SLC1A3SLC1A2SLC1A1 | |
| Aspartic Acid SCHEMBL14742505 | 0.78 | SLC1A3 (0.46) | SLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013033046-A2 | FLUORESCENT PL MARKERS FOR ISOELECTRIC FOCUSING SEPARATIONS AND FLUORESCENT LABELING | VIGH GYULA (US) | 2013-03-07 | — | — | WO | disclosed |