SCHEMBL14743606

SCHEMBL14743606

OCCCCC(O)C(O)S

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 1/20 0.35
TRPA1 O75762 1/20 0.35
CYP2D6 P10635 2/20 0.32
SPHK1 Q9NYA1 2/20 0.32
GMNN O75496 1/20 0.32
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.32
THPO P40225 1/20 0.32
MTOR P42345 1/20 0.32
BLM P54132 1/20 0.32
KDM4E B2RXH2 1/20 0.32
TP53 P04637 1/20 0.32
CYP1A2 P05177 1/20 0.32
CYP3A4 P08684 1/20 0.32
MAPT P10636 1/20 0.32
CETP P11597 1/20 0.32
HTT P42858 1/20 0.32
UBE2N P61088 1/20 0.32
PTPN1 P18031 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14742784 0.92
Acetic Acid SCHEMBL28822106 0.87 GPR84 (0.33) TRPV1TRPA1CYP2D6SPHK1GMNN
SCHEMBL14743122 0.83 TRPV1 (0.35) TRPV1TRPA1CYP2D6SPHK1GMNN
SCHEMBL3399170 0.82 TRPV1 (0.41) TRPV1TRPA1CYP2D6SPHK1GMNN
SCHEMBL24176357 0.79 TRPV1 (0.46) TRPV1TRPA1CYP2D6SPHK1GMNN
SCHEMBL1790073 0.79 TRPV1 (0.39) TRPV1TRPA1CYP2D6SPHK1GMNN
SCHEMBL21552219 0.79 TRPV1 (0.46) TRPV1TRPA1CYP2D6SPHK1GMNN
SCHEMBL21552377 0.79 TRPV1 (0.46) TRPV1TRPA1CYP2D6SPHK1GMNN
SCHEMBL4006613 0.79 TRPV1 (0.46) TRPV1TRPA1CYP2D6SPHK1GMNN
SCHEMBL5482067 0.79 TRPV1 (0.46) TRPV1TRPA1CYP2D6SPHK1GMNN

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9676907-B2 Methods and systems of graft polymerization on a functionalized substrate ASPEN RESEARCH CORPORATION (US) 2017-06-13 US disclosed
US-20160168331-A1 METHODS AND SYSTEMS OF GRAFT POLYMERIZATION ON A FUNCTIONALIZED SUBSTRATE JPMORGAN CHASE BANK, N.A., AS COLLATERAL AGENT 2016-06-16 US disclosed
US-9267009-B2 Methods and systems of graft polymerization on a functionalized substrate ASPEN RESEARCH CORPORATION (US) 2016-02-23 US disclosed
US-9074056-B2 Methods and systems to prepare functionalized substrate from disulfide bond-containing material ASPEN RESEARCH CORPORATION (US) 2015-07-07 US disclosed
US-20140343188-A1 METHODS AND SYSTEMS TO PREPARE FUNCTIONALIZED SUBSTRATE FROM DISULFIDE BOND-CONTAINING MATERIAL ASPEN RESEARCH CORPORATION (US) 2014-11-20 US disclosed
US-20140296366-A1 METHODS AND SYSTEMS OF GRAFT POLYMERIZATION ON A FUNCTIONALIZED SUBSTRATE ASPEN RESEARCH CORPORATION (US) 2014-10-02 US disclosed
WO-2013033614-A1 METHODS AND SYSTEMS TO PREPARE FUNCTIONALIZED SUBSTRATE FROM DISULFIDE BOND-CONTAINING MATERIAL ASPEN RESEARCH CORPORATION (US) 2013-03-07 WO disclosed
WO-2013033610-A1 METHODS AND SYSTEMS OF GRAFT POLYMERIZATION ON A FUNCTIONALIZED SUBSTRATE ASPEN RESEARCH CORPORATION (US) 2013-03-07 WO disclosed