Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 19/20 | 0.72 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.57 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.57 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.56 |
| ▸ | HTR2C | P28335 | 1/20 | 0.56 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.56 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.56 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.56 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14746788 | 0.93 | RORC (0.77) | RORCCYP2C9CYP2C19 | |
| SCHEMBL14744113 | 0.88 | RORC (0.81) | RORCCYP2C9CYP2C19 | |
| SCHEMBL15392018 | 0.88 | RORC (0.69) | RORCCYP2C9CYP2C8CYP2D6ADRA2B | |
| SCHEMBL15391798 | 0.88 | RORC (0.69) | RORCCYP2C9CYP2C8CYP2D6ADRA2B | |
| SCHEMBL15391977 | 0.87 | P2RX4 (0.60) | RORCCYP2C9CYP2C8CYP2D6ADRA2B | |
| SCHEMBL15392516 | 0.87 | RORC (0.64) | RORCCYP2C9CYP2C8CYP2D6ADRA2B | |
| SCHEMBL15392850 | 0.86 | P2RX4 (0.63) | RORCCYP2C9CYP2C8CYP2D6ADRA2B | |
| SCHEMBL15392836 | 0.85 | RORC (0.70) | RORCCYP2C9CYP2C19 | |
| SCHEMBL15391231 | 0.85 | RORC (0.56) | RORCCYP2C9CYP2C8CYP2D6ADRA2B | |
| SCHEMBL15392310 | 0.84 | RORC (0.62) | RORCCYP2C9CYP2C8CYP2D6ADRA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |