Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NCOA1 | Q15788 | 1/20 | 0.51 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.51 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.50 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.50 |
| ▸ | FEN1 | P39748 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.49 |
| ▸ | SCN9A | Q15858 | 11/20 | 0.47 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | MME | P08473 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL306822 | 0.84 | FFAR4 (0.55) | FFAR4ALOX5APFEN1TRPA1SCN9A | |
| SCHEMBL29788132 | 0.84 | FFAR4 (0.55) | FFAR4ALOX5APFEN1TRPA1SCN9A | |
| SCHEMBL1045874 | 0.83 | FFAR4 (0.51) | FFAR4ALOX5APFEN1TRPA1SCN9A | |
| SCHEMBL27784743 | 0.83 | MPL (0.40) | NCOA1NCOA3FFAR4ALOX5APFEN1 | |
| SCHEMBL2141965 | 0.81 | GLA (0.42) | NCOA1NCOA3FFAR4ALOX5APFEN1 | |
| SCHEMBL2095253 | 0.81 | FFAR4 (0.50) | FFAR4ALOX5APFEN1TRPA1SCN9A | |
| SCHEMBL12570859 | 0.81 | FFAR4 (0.47) | FFAR4ALOX5APFEN1TRPA1SCN9A | |
| SCHEMBL8221610 | 0.81 | FFAR4 (0.50) | FFAR4ALOX5APFEN1TRPA1SCN9A | |
| SCHEMBL977930 | 0.81 | SCN9A (0.56) | ALOX5APFEN1TRPA1SCN9ACYP3A4 | |
| Hydrochloric Acid SCHEMBL28045031 | 0.80 | GLA (0.41) | NCOA1NCOA3FFAR4ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |