SCHEMBL306822

SCHEMBL306822

FC(F)(F)Oc1ccccc1-c1ccccc1

nearest known ligand 0.55

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 1/20 0.55
SCN9A Q15858 10/20 0.54
TRPA1 O75762 1/20 0.50
L3MBTL1 Q9Y468 2/20 0.48
KDM4E B2RXH2 1/20 0.48
MAPT P10636 1/20 0.48
ALDH1A1 P00352 1/20 0.45
HSD11B1 P28845 1/20 0.45
MME P08473 1/20 0.45
CYP2C9 P11712 2/20 0.45
CYP3A4 P08684 1/20 0.45
CYP2D6 P10635 1/20 0.45
ALOX5AP P20292 1/20 0.44
FEN1 P39748 1/20 0.44
TP53 P04637 1/20 0.44
MAPK1 P28482 1/20 0.44
RAB9A P51151 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29788132 1.00 FFAR4 (0.55) FFAR4SCN9ATRPA1L3MBTL1KDM4E
Benzenethiol SCHEMBL29098921 0.91 FFAR4 (0.49) FFAR4SCN9ATRPA1L3MBTL1KDM4E
SCHEMBL29991270 0.87 FFAR4 (0.46) FFAR4SCN9ATRPA1L3MBTL1KDM4E
SCHEMBL7701143 0.86 ALDH1A1 (0.50) FFAR4SCN9ATRPA1L3MBTL1KDM4E
SCHEMBL1045874 0.86 FFAR4 (0.51) FFAR4SCN9ATRPA1L3MBTL1ALDH1A1
SCHEMBL25219191 0.84 SCN9A (0.46) FFAR4SCN9ATRPA1L3MBTL1KDM4E
SCHEMBL699801 0.84 FFAR4 (0.47) FFAR4SCN9ATRPA1L3MBTL1KDM4E
SCHEMBL2095253 0.84 FFAR4 (0.50) FFAR4SCN9ATRPA1L3MBTL1KDM4E
SCHEMBL14744155 0.84 NCOA1 (0.51) FFAR4SCN9ATRPA1MMECYP2C9
SCHEMBL615003 0.84 SCN9A (0.51) FFAR4SCN9ATRPA1L3MBTL1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 62 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114230552-B Trifluoromethoxy dibenzothiophene, preparation method thereof and preparation method of related intermediate 江苏广域化学有限公司 2023-11-03 CN claimed
CN-115028835-A Hydrophobic polyimide foam and preparation method thereof 中国科学院大连化学物理研究所 2022-09-09 CN claimed
CN-114230552-A Trifluoromethoxy dibenzothiophene, preparation method thereof and preparation method of related intermediate 江苏广域化学有限公司 2022-03-25 CN claimed
CN-113072702-A Colorless transparent copolymerized polyimide film and preparation method thereof 上海大学(浙江·嘉兴)新兴产业研究院 2021-07-06 CN claimed
WO-2007117482-A2 RENIN INHIBITORS VITAE PHARMACEUTICALS, INC. (US) 2007-10-18 WO claimed
CN-1898222-A Substituted aryl cycloalkanol derivatives and methods of their use WYETH CORP (US) 2007-01-17 CN claimed
JP-9124569-A None JP disclosed
CN-115960380-B Polyimide composite film and preparation method and application thereof 中国石油化工股份有限公司 2024-06-28 CN disclosed
CN-114907361-B Trimeric heterocyclic derivative and application thereof 北京八亿时空液晶科技股份有限公司 2024-06-04 CN disclosed
CN-117043304-A Aromatic isothiocyanates 默克专利股份有限公司 2023-11-10 CN disclosed
CN-114230552-B Trifluoromethoxy dibenzothiophene, preparation method thereof and preparation method of related intermediate 江苏广域化学有限公司 2023-11-03 CN disclosed
CN-116730845-A High-fluorine-content biphenyl diamine, colorless polyimide optical film, and preparation method and application thereof 华南理工大学 2023-09-12 CN disclosed
WO-2023101004-A1 OLEFIN RESIN, METHOD FOR MANUFACTURING SAME, AND APPLICATION FOR SAME 三井化学株式会社 2023-06-08 WO disclosed
WO-1996028491-A1 SOLUBLE FLUORINATED POLY-P-PHENYLENES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-09-19 WO disclosed
CN-1112575-A Diaminobenzene derivatives and polyimides prepared therefrom NISSAN CHEMICAL IND LTD (JP) 1995-11-29 CN disclosed
EP-0682283-A1 Liquid crystal alignment film NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1995-11-15 EP disclosed
EP-0679633-A1 Diaminobenzene derivatives and polyimides prepared therefrom NISSAN CHEMICAL INDUSTRIES LTD. (JP) 1995-11-02 EP disclosed
US-5322917-A Fluorine-containing diamines polyamides, and polyimides E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-06-21 US disclosed
EP-0601063-A1 FLUORINE-CONTAINING DIAMINES, POLYAMIDES, AND POLYIMIDES. DU PONT (US) 1994-06-15 EP disclosed
WO-1993004033-A1 FLUORINE-CONTAINING DIAMINES, POLYAMIDES, AND POLYIMIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1993-03-04 WO disclosed