Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 20/20 | 0.83 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.68 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14744190 | 0.91 | RORC (1.00) | RORCCYP2C9CYP2C19 | |
| SCHEMBL20943206 | 0.86 | RORC (1.00) | RORCCYP2C9CYP2C19 | |
| SCHEMBL14746836 | 0.85 | RORC (0.88) | RORCCYP2C9CYP2C19 | |
| SCHEMBL14746481 | 0.84 | RORC (0.83) | RORCCYP2C9CYP2C19 | |
| SCHEMBL14746393 | 0.84 | RORC (0.86) | RORCCYP2C9CYP2C19 | |
| SCHEMBL14754265 | 0.83 | RORC (1.00) | RORCCYP2C9CYP2C19 | |
| SCHEMBL14744539 | 0.83 | RORC (0.84) | RORCCYP2C9CYP2C19 | |
| SCHEMBL14744505 | 0.82 | RORC (0.77) | RORCCYP2C9CYP2C19 | |
| SCHEMBL14746931 | 0.82 | RORC (0.72) | RORCCYP2C9CYP2C19 | |
| SCHEMBL14744232 | 0.82 | RORC (1.00) | RORCCYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |
| WO-2013029338-A1 | NOVEL COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2013-03-07 | — | — | WO | disclosed |