SCHEMBL14744231

SCHEMBL14744231

CCS(=O)(=O)c1ccc(CC(=O)Nc2ccc(-c3cc(Cl)ccc3Cl)c(Cl)c2)cc1

nearest known ligand 0.82

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RORC P51449 20/20 0.82

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14746619 0.90 RORC (1.00) RORC
SCHEMBL14754228 0.89 RORC (0.75) RORC
SCHEMBL14746498 0.88 RORC (0.70) RORC
SCHEMBL14744499 0.88 RORC (0.73) RORC
SCHEMBL14743998 0.88 RORC (1.00) RORC
SCHEMBL14754295 0.87 RORC (0.78) RORC
SCHEMBL14746661 0.86 RORC (1.00) RORC
SCHEMBL14744232 0.85 RORC (1.00) RORC
SCHEMBL14754238 0.85 RORC (0.86) RORC
SCHEMBL14746833 0.85 RORC (0.86) RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013029338-A1 NOVEL COMPOUNDS GLAXO GROUP LIMITED (GB) 2013-03-07 WO disclosed