SCHEMBL14744283

SCHEMBL14744283

CC(=O)Nc1ccc(Br)c(OC(F)(F)F)c1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.51
EPHX2 P34913 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.49
RECQL P46063 1/20 0.48
EPHX1 P07099 1/20 0.47
CYP1A2 P05177 1/20 0.47
CYP2C9 P11712 1/20 0.47
CYP2C19 P33261 1/20 0.47
RORC P51449 1/20 0.46
HDAC1 Q13547 1/20 0.46
HDAC7 Q8WUI4 1/20 0.46
HDAC8 Q9BY41 1/20 0.46
HDAC6 Q9UBN7 1/20 0.46
IDO1 P14902 1/20 0.45
TDO2 P48775 1/20 0.45
KDM4E B2RXH2 2/20 0.44
MEN1 O00255 2/20 0.44
NPC1 O15118 2/20 0.44
MAPT P10636 2/20 0.44
RAB9A P51151 2/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29362736 1.00 ALDH1A1 (0.51) ALDH1A1EPHX2L3MBTL1RECQLEPHX1
SCHEMBL28949066 0.89 SMN1; SMN2 (0.51) ALDH1A1EPHX2L3MBTL1RECQLHDAC1
SCHEMBL4855842 0.88 ALDH1A1 (0.55) ALDH1A1EPHX2L3MBTL1RECQLEPHX1
SCHEMBL15168933 0.86 EPHX2 (0.51) ALDH1A1EPHX2EPHX1CYP1A2CYP2C9
SCHEMBL6153688 0.83 EPHX2 (0.46) ALDH1A1EPHX2CYP1A2CYP2C9CYP2C19
SCHEMBL30675566 0.82 CYP1A2 (0.66) ALDH1A1EPHX2L3MBTL1RECQLCYP1A2
SCHEMBL879728 0.81 GRM4 (0.59) ALDH1A1KDM4EMEN1NPC1MAPT
SCHEMBL30159535 0.81 GRM4 (0.59) ALDH1A1KDM4EMEN1NPC1MAPT
SCHEMBL23419127 0.80 EPHX2 (0.77) ALDH1A1EPHX2L3MBTL1RECQLCYP1A2
SCHEMBL21649325 0.80 ALDH1A1 (0.56) ALDH1A1EPHX2L3MBTL1RECQLCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12227620-B2 Polymers for use in electronic devices DUPONT ELECTRONICS, INC. (US) 2025-02-18 US disclosed
CN-113993931-B Polymer for use in electronic devices 杜邦电子公司 2024-01-23 CN disclosed
US-20220325045-A1 POLYMERS FOR USE IN ELECTRONIC DEVICES U.S. BANK TRUST COMPANY, NATIONAL ASSOCIATION, AS NOTES COLLATERAL AGENT 2022-10-13 US disclosed
CN-113993931-A Polymers for use in electronic devices 杜邦电子公司 2022-01-28 CN disclosed
WO-2020219411-A1 POLYMERS FOR USE IN ELECTRONIC DEVICES DUPONT ELECTRONICS, INC. (US) 2020-10-29 WO disclosed
WO-2020219411-A1 POLYMERS FOR USE IN ELECTRONIC DEVICES DUPONT ELECTRONICS, INC. (US) 2020-10-29 WO disclosed
WO-2013029338-A1 NOVEL COMPOUNDS GLAXO GROUP LIMITED (GB) 2013-03-07 WO disclosed