SCHEMBL14744508

SCHEMBL14744508

CCS(=O)(=O)c1ccc(CC(=O)Nc2cc(F)c(-c3ccccc3)c(F)c2)cc1

nearest known ligand 0.76

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RORC P51449 20/20 0.76

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14744106 0.92 RORC (0.86) RORC
SCHEMBL14754254 0.86 RORC (1.00) RORC
SCHEMBL14754211 0.85 RORC (0.59) RORC
SCHEMBL14754235 0.85 RORC (0.59) RORC
SCHEMBL14744546 0.83 RORC (0.59) RORC
SCHEMBL14754266 0.83 RORC (0.69) RORC
SCHEMBL14746502 0.83 RORC (0.63) RORC
SCHEMBL14746756 0.82 RORC (0.79) RORC
SCHEMBL14744277 0.81 RORC (0.60) RORC
SCHEMBL14744195 0.81 RORC (0.57) RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013029338-A1 NOVEL COMPOUNDS GLAXO GROUP LIMITED (GB) 2013-03-07 WO disclosed
WO-2013029338-A1 NOVEL COMPOUNDS GLAXO GROUP LIMITED (GB) 2013-03-07 WO disclosed