Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAPK3 | O43293 | 1/20 | 0.30 |
| ▸ | RET | P07949 | 1/20 | 0.30 |
| ▸ | PRKACA | P17612 | 1/20 | 0.30 |
| ▸ | GRK5 | P34947 | 1/20 | 0.30 |
| ▸ | CDK8 | P49336 | 1/20 | 0.30 |
| ▸ | GSK3A | P49840 | 1/20 | 0.30 |
| ▸ | GSK3B | P49841 | 1/20 | 0.30 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.30 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.30 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.30 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.30 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.30 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7738629 | 0.80 | NOS2 (0.38) | — | |
| SCHEMBL5263086 | 0.75 | ABCG2 (0.44) | DAPK3RETPRKACAGRK5CDK8 | |
| Hydrochloric Acid SCHEMBL12469273 | 0.73 | ABCG2 (0.42) | DAPK3RETPRKACAGRK5CDK8 | |
| Acetic Acid SCHEMBL27604418 | 0.68 | NOTUM (0.49) | — | |
| SCHEMBL30738537 | 0.61 | CA12 (0.34) | PRKACAPRKCQ | |
| SCHEMBL7613241 | 0.61 | KDM4E (0.43) | — | |
| SCHEMBL30692889 | 0.61 | CA12 (0.52) | PRKACAPRKCQ | |
| SCHEMBL8229991 | 0.61 | CA12 (0.52) | PRKACAPRKCQ | |
| SCHEMBL28319074 | 0.61 | CA12 (0.34) | PRKACAPRKCQ | |
| SCHEMBL26103119 | 0.59 | ITGB2 (0.52) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2013033245-A1 | BICYCLIC METHYLENE AZIRIDINES AND REACTIONS THEREOF | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2013-03-07 | — | — | WO | disclosed |