Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 18/20 | 0.37 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | MGAM | O43451 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | SI | P14410 | 1/20 | 0.36 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14745509 | 0.89 | GPR119 (0.36) | GPR119MGLLMGAMGAASI | |
| SCHEMBL17597372 | 0.86 | GSK3B (0.40) | — | |
| SCHEMBL14740812 | 0.82 | GPR119 (0.49) | GPR119 | |
| SCHEMBL14740956 | 0.81 | GPR119 (0.53) | GPR119 | |
| SCHEMBL14745036 | 0.80 | GSK3B (0.47) | — | |
| SCHEMBL14744616 | 0.76 | GSK3B (0.49) | — | |
| SCHEMBL17597373 | 0.74 | GSK3B (0.39) | GAA | |
| SCHEMBL16428826 | 0.74 | GPR119 (0.46) | GPR119 | |
| SCHEMBL14757758 | 0.73 | GPR119 (0.48) | GPR119 | |
| SCHEMBL17597693 | 0.73 | PTGER3 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2750504-A1 | ANTIBACTERIAL COMPOUNDS AND METHODS FOR USE | PTC Therapeutics, Inc. (US) | 2014-07-09 | — | — | EP | claimed |
| WO-2013033258-A1 | ANTIBACTERIAL COMPOUNDS AND METHODS FOR USE | PTC THERAPEUTICS, INC. (US) | 2013-03-07 | — | — | WO | claimed |