Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 13/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11525795 | 0.76 | EPHX1 (0.48) | EPHX1ACHEALDH1A1POLBATM | |
| SCHEMBL16279015 | 0.76 | PTPRB (0.43) | CYP1A2CYP2C19 | |
| SCHEMBL16279014 | 0.76 | PTPRB (0.43) | CYP1A2CYP2C19 | |
| SCHEMBL4669846 | 0.76 | EPHX1 (0.44) | EPHX1ACHEALDH1A1POLBATM | |
| SCHEMBL2487393 | 0.75 | EPHX1 (0.47) | EPHX1ACHEALDH1A1POLBATM | |
| SCHEMBL1504663 | 0.74 | EPHX1 (0.43) | EPHX1ACHEALDH1A1NPC1CASP1 | |
| SCHEMBL2486965 | 0.73 | EPHX1 (0.46) | EPHX1ACHEALDH1A1POLBATM | |
| SCHEMBL12292607 | 0.73 | ATM (0.43) | EPHX1ACHEPOLBATMHCAR2 | |
| SCHEMBL5492611 | 0.72 | POLB (0.46) | EPHX1ACHEALDH1A1POLBATM | |
| SCHEMBL7368744 | 0.72 | EPHX1 (0.44) | EPHX1ACHEALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2751124-A1 | VERSATILE AND STEREOSPECIFIC SYNTHESIS OF GAMMA,DELTA -UNSATURATED AMINO ACIDS BY WITTIG REACTION | Centre National de la Recherche Scientifique (CNRS) (FR) | 2014-07-09 | — | — | EP | disclosed |
| WO-2013030193-A1 | VERSATILE AND STEREOSPECIFIC SYNTHESIS OF GAMMA,DELTA -UNSATURATED AMINO ACIDS BY WITTIG REACTION | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (CNRS) (FR) | 2013-03-07 | — | — | WO | disclosed |