Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 12/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10476092 | 1.00 | EPHX1 (0.44) | EPHX1ACHEALDH1A1RAB9ANPC1 | |
| SCHEMBL1504663 | 0.85 | EPHX1 (0.43) | EPHX1ACHEALDH1A1RAB9ANPC1 | |
| SCHEMBL9030664 | 0.83 | EPHX1 (0.42) | EPHX1ACHEALDH1A1RAB9ANPC1 | |
| SCHEMBL2487393 | 0.82 | EPHX1 (0.47) | EPHX1ACHEALDH1A1POLBATM | |
| SCHEMBL5201837 | 0.81 | EPHX1 (0.43) | EPHX1ACHEALDH1A1RAB9APOLB | |
| SCHEMBL3400195 | 0.81 | EPHX1 (0.43) | EPHX1ACHEALDH1A1POLBATM | |
| SCHEMBL2486965 | 0.81 | EPHX1 (0.46) | EPHX1ACHEALDH1A1POLBATM | |
| SCHEMBL11525795 | 0.80 | EPHX1 (0.48) | EPHX1ACHEALDH1A1POLBATM | |
| SCHEMBL11100479 | 0.80 | EPHX1 (0.52) | EPHX1ACHEALDH1A1RAB9ANPC1 | |
| SCHEMBL5492611 | 0.79 | POLB (0.46) | EPHX1ACHEALDH1A1POLBATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1224186-A2 | PYRIDYL-CONTAINING SPIROCYCLIC COMPOUNDS AS INHIBITORS OF FIBRINOGEN-DEPENDENT PLATELET AGGREGATION | COR THERAPEUTICS, INC. (US) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001030780-A2 | PYRIDYL-CONTAINING SPIROCYCLIC COMPOUNDS AS INHIBITORS OF FIBRINOGEN-DEPENDENT PLATELET AGGREGATION | COR THERAPEUTICS, INC. (US) | 2001-05-03 | — | — | WO | disclosed |