Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 20/20 | 0.75 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14747208 | 0.95 | KIT (0.73) | KIT | |
| SCHEMBL14757524 | 0.93 | KIT (0.74) | KIT | |
| SCHEMBL14741442 | 0.90 | KIT (0.79) | KIT | |
| SCHEMBL27337673 | 0.90 | KIT (0.79) | KIT | |
| SCHEMBL21387286 | 0.90 | KIT (0.80) | KIT | |
| SCHEMBL14741625 | 0.90 | KIT (0.72) | KIT | |
| SCHEMBL14741854 | 0.90 | KIT (0.74) | KIT | |
| SCHEMBL14757491 | 0.89 | KIT (0.78) | KIT | |
| SCHEMBL14741582 | 0.89 | KIT (0.77) | KIT | |
| SCHEMBL14741815 | 0.89 | KIT (0.77) | KIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2751103-A1 | COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS | IRM LLC (BM) | 2014-07-09 | — | — | EP | disclosed |
| EP-2751104-A1 | COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS | IRM LLC (BM) | 2014-07-09 | — | — | EP | disclosed |
| WO-2013033116-A1 | COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS | IRM LLC (BM) | 2013-03-07 | — | — | WO | disclosed |
| WO-2013033167-A1 | COMPOUNDS AND COMPOSITIONS AS C-KIT KINASE INHIBITORS | IRM LLC (BM) | 2013-03-07 | — | — | WO | disclosed |