Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 6/20 | 0.35 |
| ▸ | CA2 | P00918 | 4/20 | 0.35 |
| ▸ | CA9 | Q16790 | 4/20 | 0.35 |
| ▸ | CA7 | P43166 | 3/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | TACR1 | P25103 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.33 |
| ▸ | CA4 | P22748 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14372181 | 1.00 | CA1 (0.35) | CA1CA2CA9CA7TSHR | |
| SCHEMBL754270 | 1.00 | CA1 (0.35) | CA1CA2CA9CA7TSHR | |
| SCHEMBL9344087 | 1.00 | CA1 (0.35) | CA1CA2CA9CA7TSHR | |
| SCHEMBL14747292 | 1.00 | CA1 (0.35) | CA1CA2CA9CA7TSHR | |
| SCHEMBL15721047 | 0.97 | CA1 (0.35) | CA1CA2CA9CA7TSHR | |
| SCHEMBL4619157 | 0.97 | CA1 (0.35) | CA1CA2CA9CA7TSHR | |
| SCHEMBL4619145 | 0.97 | CA1 (0.35) | CA1CA2CA9CA7TSHR | |
| SCHEMBL4621789 | 0.97 | CA1 (0.35) | CA1CA2CA9CA7TSHR | |
| SCHEMBL6102167 | 0.87 | TBXAS1 (0.44) | CA1CA2MMP2MMP3 | |
| SCHEMBL15892827 | 0.87 | CA1 (0.42) | CA1CA2CA9CA7TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389565-B2 | Antidiabetic agents; controlling carbohydrate metabolism | SIMON FRASER UNIVERSITY (CA) | 2013-03-05 | — | — | US | disclosed |