SCHEMBL14747378

SCHEMBL14747378

CCC(C)(C)C(=O)Oc1cc(C)cc(C)c1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.42
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
CNR2 P34972 3/20 0.39
MAPT P10636 1/20 0.38
THRB P10828 1/20 0.38
HPGD P15428 2/20 0.37
KDM4E B2RXH2 1/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
ALDH1A1 P00352 1/20 0.35
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35
MAPK1 P28482 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
GAA P10253 1/20 0.35
LMNA P02545 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.33
TPMT P51580 1/20 0.33
HTT P42858 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15395795 0.91 ELANE (0.40) ELANEMEN1KMT2ACNR2MAPT
SCHEMBL106972 0.86 MAPT (0.37) ELANECNR2MAPTALDH1A1LMNA
SCHEMBL17264838 0.85 ELANE (0.35) ELANEMEN1KMT2ACNR2KDM4E
SCHEMBL2757698 0.84 ELANE (0.47) ELANECNR2LMNA
SCHEMBL12736994 0.84 ELANE (0.41) ELANECNR2HPGDLMNASMN1; SMN2
SCHEMBL15043140 0.83 ELANE (0.44) ELANEMEN1KMT2AMAPTCYP3A4
SCHEMBL15495839 0.83 LMNA (0.57) MEN1KMT2AMAPTL3MBTL1ALDH1A1
SCHEMBL8738351 0.82 ESR1 (0.44) ELANEMEN1KMT2AHPGDALDH1A1
SCHEMBL12736999 0.81 ELANE (0.54) ELANEMEN1KMT2AHPGDL3MBTL1
SCHEMBL17585017 0.80 ELANE (0.55) ELANEMEN1KMT2AMAPTTHRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8389200-B2 Pattern forming method FUJIFILM CORPORATION (JP) 2013-03-05 US disclosed