Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.56 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.56 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.56 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | CASP7 | P55210 | 1/20 | 0.46 |
| ▸ | SMAD3 | P84022 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20863104 | 0.83 | CHRM2 (0.52) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL15871059 | 0.81 | CHRM2 (0.53) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL10020224 | 0.80 | CHRM2 (0.54) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL10216047 | 0.76 | KDM4E (0.54) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL14564422 | 0.76 | CHRM2 (0.71) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL5905885 | 0.76 | CHRM2 (0.56) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL12656456 | 0.75 | CHRM2 (0.70) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 | |
| SCHEMBL19871386 | 0.75 | HSD17B10 (0.53) | ALDH1A1KDM4ENOTUMMEN1KMT2A | |
| SCHEMBL19871390 | 0.74 | HDAC1 (0.53) | ALDH1A1KDM4ENOTUMMEN1KMT2A | |
| SCHEMBL12956755 | 0.73 | ALDH1A1 (0.59) | CHRM2CHRM4CHRM1CHRM3ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389729-B2 | Methods for detecting the presence, location or quantity of targets using novel dyes | ENZO LIFE SCIENCES, INC. (US) | 2013-03-05 | — | — | US | disclosed |