Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | INSR | P06213 | 15/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.35 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.35 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.35 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | NSD2 | O96028 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1105772 | 0.86 | INSR (0.52) | INSR | |
| SCHEMBL9415719 | 0.71 | CNR2 (0.41) | INSRCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9100255 | 0.69 | INSR (0.42) | INSRCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9103150 | 0.69 | INSR (0.42) | INSRCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9098540 | 0.69 | INSR (0.42) | INSRCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9100970 | 0.69 | INSR (0.45) | INSRCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9100973 | 0.69 | INSR (0.45) | INSRCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL9097822 | 0.68 | CHRM2 (0.42) | INSRCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL7719119 | 0.68 | CHRM2 (0.54) | INSRCHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL16183109 | 0.67 | CHRM2 (0.55) | INSRCHRM2CHRM4CHRM5CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389729-B2 | Methods for detecting the presence, location or quantity of targets using novel dyes | ENZO LIFE SCIENCES, INC. (US) | 2013-03-05 | — | — | US | disclosed |