Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 5/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | CYP4F2 | P78329 | 4/20 | 0.48 |
| ▸ | CYP4A11 | Q02928 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | PLK1 | P53350 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10272652 | 0.94 | RAB9A (0.58) | FFAR1RAB9ACYP4F2CYP4A11MAPK1 | |
| SCHEMBL2776604 | 0.88 | FFAR1 (0.55) | FFAR1CYP4F2CYP4A11L3MBTL1TSHR | |
| SCHEMBL2776602 | 0.88 | FFAR1 (0.55) | FFAR1CYP4F2CYP4A11L3MBTL1TSHR | |
| SCHEMBL12577538 | 0.86 | FFAR1 (0.53) | FFAR1RAB9ACYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL12976712 | 0.82 | RAB9A (0.46) | RAB9AALDH1A1MAPTLMNAL3MBTL1 | |
| SCHEMBL31729334 | 0.82 | FFAR1 (0.52) | FFAR1RAB9ACYP4F2CYP4A11MAPT | |
| SCHEMBL15091893 | 0.82 | FFAR1 (0.52) | FFAR1RAB9ACYP4F2CYP4A11MAPT | |
| SCHEMBL14882215 | 0.80 | FFAR1 (0.48) | FFAR1RAB9ACYP4F2CYP4A11MAPT | |
| SCHEMBL14880570 | 0.80 | FFAR1 (0.48) | FFAR1RAB9ACYP4F2CYP4A11MAPT | |
| SCHEMBL10289077 | 0.79 | RAB9A (0.57) | FFAR1RAB9AALDH1A1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8389580-B2 | Arylcyclopropylamines and methods of use | DUKE UNIVERSITY (US) | 2013-03-05 | — | — | US | disclosed |