Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6349545 | 0.84 | PTGS2 (0.67) | PTGS2PTGS1 | |
| SCHEMBL13238794 | 0.83 | PTGS2 (0.47) | PTGS2PTGS1 | |
| SCHEMBL5698714 | 0.81 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL6659189 | 0.81 | CCNA2 (0.64) | PTGS2PTGS1 | |
| SCHEMBL6343720 | 0.79 | PTGS2 (0.66) | PTGS2PTGS1 | |
| SCHEMBL6339161 | 0.78 | PTGS2 (0.74) | PTGS2PTGS1 | |
| SCHEMBL6353347 | 0.76 | PTGS2 (0.72) | PTGS2PTGS1 | |
| SCHEMBL6349858 | 0.76 | PTGS2 (0.63) | PTGS2PTGS1 | |
| SCHEMBL8933820 | 0.76 | PTGS2 (1.00) | PTGS2PTGS1 | |
| SCHEMBL6660718 | 0.76 | CA9 (0.55) | PTGS2PTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE44048-E1 | 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-YL]benzenesulfonamide for the treatment of inflammation or an inflammation-associated disorder | G.D. SEARLE LLC (US) | 2013-03-05 | — | — | US | disclosed |
| US-RE44048-E1 | 4-[5-(4-methylphenyl)-3-(trifluoromethyl)-1H-pyrazol-1-YL]benzenesulfonamide for the treatment of inflammation or an inflammation-associated disorder | G.D. SEARLE LLC (US) | 2013-03-05 | — | — | US | disclosed |